Genetic Modifiers: Lessons from Nervous System Disorders

This workshop will bring together a diverse group of researchers with expertise in genetics, genomics, neurology, pathophysiology, and preclinical translation. Understanding genetic factors that modify the onset, progression or severity of diseases can lead to novel therapeutics, facilitate clinical trial design, and enable personalized medicine. The purpose of this workshop is to promote collaborations, confront challenges and highlight successful strategies for genetic modifier discovery, validation, and clinical implementation as part of the NIH Blueprint mission to foster transformative discoveries in neuroscience.