{"id":5222,"date":"2023-10-04T19:48:42","date_gmt":"2023-10-04T19:48:42","guid":{"rendered":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/?p=5222"},"modified":"2023-10-04T19:48:44","modified_gmt":"2023-10-04T19:48:44","slug":"alejandro-alex-chibly","status":"publish","type":"post","link":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/alejandro-alex-chibly\/","title":{"rendered":"Alejandro (Alex) Chibly"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-content\/uploads\/sites\/63\/2023\/10\/Alex-Chibly-resize.png\" alt=\"\" class=\"wp-image-5223\" srcset=\"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-content\/uploads\/sites\/63\/2023\/10\/Alex-Chibly-resize.png 300w, https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-content\/uploads\/sites\/63\/2023\/10\/Alex-Chibly-resize-150x150.png 150w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/figure>\n\n\n\n<p>Bioinformatics Scientist in Reverse Translation (Oncology signaling) and Oncology Bioinformatics. My main areas of focus include hormone receptor-positive breast and prostate cancer biology, as well as mechanisms of response and resistance to endocrine therapy, CDK4\/6i and PI3Ki. I specialize in the analysis of transcriptomic and genomic data from patient-derived tumors using regression and machine learning tools to identify actionable targets for potential use in combination therapies, and to understand mechanisms of inherent and acquired resistance to cancer therapies. I got a PhD in Cancer Biology from the University of Arizona in the laboratory of Dr. Kirsten Limesand, and did a post-doc training at the National Institute of Dental and Craniofacial Research (NIDCR\/NIH) with Dr. Matt Hoffman. My previous research focused on investigating molecular mechanisms associated with salivary gland dysfunction that occurs as a consequence of cancer radiotherapy, where I led the generation of a single-cell RNAseq atlas of salivary gland development, and the transcriptional profiling of human irradiated salivary glands to identify clinically relevant targets to develop curative strategies for loss of saliva.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bioinformatics Scientist in Reverse Translation (Oncology signaling) and Oncology Bioinformatics. My main areas of focus include hormone receptor-positive breast and prostate cancer biology, as well as mechanisms of response and resistance to endocrine therapy, CDK4\/6i and PI3Ki. I specialize in the analysis of transcriptomic and genomic data from patient-derived tumors using regression and machine learning&#8230;<\/p>\n","protected":false},"author":6,"featured_media":5223,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5222","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/posts\/5222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/comments?post=5222"}],"version-history":[{"count":1,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/posts\/5222\/revisions"}],"predecessor-version":[{"id":5224,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/posts\/5222\/revisions\/5224"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/media\/5223"}],"wp:attachment":[{"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/media?parent=5222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/categories?post=5222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/event.roseliassociates.com\/nidcr-trainee-symposium\/wp-json\/wp\/v2\/tags?post=5222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}