Dr. Yi Li is a professor at the Lester & Sue Smith Breast Center and the Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas. His lab investigates the molecular and cellular mechanisms of breast cancer initiation and progression. In particular, his lab has developed multiple mouse and rat models of breast cancer that closely mimic human breast cancer initiation and progression. His preclinical work on intermittent anti-JAK treatment for preventing breast cancer has resulted in a multi-center window-of-opportunity clinical trial (TBCRC042).