{"id":4093,"date":"2022-10-04T15:34:21","date_gmt":"2022-10-04T15:34:21","guid":{"rendered":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/?p=4093"},"modified":"2022-10-05T15:36:06","modified_gmt":"2022-10-05T15:36:06","slug":"diego-v-bohorquez","status":"publish","type":"post","link":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/diego-v-bohorquez\/","title":{"rendered":"Diego V. Boh\u00f3rquez"},"content":{"rendered":"<p><a href=\"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-content\/uploads\/sites\/44\/2022\/10\/Digeo-Bohorquez.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft wp-image-4087 size-full\" src=\"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-content\/uploads\/sites\/44\/2022\/10\/Digeo-Bohorquez.jpg\" alt=\"\" width=\"300\" height=\"300\" \/><\/a><\/p>\n<p>Dr. Boh\u00f3rquez is an Associate Professor of Medicine and Neurobiology at Duke University. Dr. Boh\u00f3rquez\u2019s expertise is in gut-brain sensory transduction. This new field of sensory biology was sparked by Dr. Boh\u00f3rquez\u2019s discovery of synapses in enteroendocrine cells in 2015. Dr. Boh\u00f3rquez discovery of a sensory neuroepithelial circuit in the gut (<em>J Clin Invest. 2015;125(2):782<\/em>)\u2014analogous to that transducing the sense of taste in the tongue\u2014has been featured in Nature, TED ideas blog and The New Yorker.<\/p>\n<p>Dr. Boh\u00f3rquez opened his laboratory in the fall of 2015. On September 21<sup>st<\/sup>, 2018, his laboratory published a research article in <em>Science<\/em> magazine documenting a neural circuit for the gut to transduce a sense to the brain in milliseconds using glutamate as a neurotransmitter. The circuit is formed by a synaptic link between enteroendocrine cells and the vagus nerve. To account for their neurotransmission function, these gut sensory cells are referred to as neuropod cells. They form the basis of a gut sense that exchanges signals with the brain in real time. This discovery is a paradigm shift in our understanding of how the gut senses nutrients because so far only slow endocrine mechanisms have been described. More recently, Dr. Boh\u00f3rquez and his team discovered that neuropod cells are necessary and sufficient to drive sugar preferences (<em>Buchanan, Rupprecht, Kaelberer et al. 2022. Nature Neurosci<\/em>). These discoveries stablished how the gut detects, encodes, and transmits signals from sugars to the brain so an animal can adjust its consumption of the most prevalent macronutrient in nature. This work also uncovered a potential portal for microbial pathogens to access the peripheral and central nervous systems.<\/p>\n<p>Dr. Boh\u00f3rquez\u2019s work has been recognized by multiple prestigious awards, including: Grass Fellowship in the Neurosciences, Kavli Fellow, Polak Young Investigator Award from the American Association for Chemoreception Sciences, TED Fellows Award, NIH F32 Postdoctoral Fellowship, NIH K01 Career Development Award, and NIH DP2 New Innovator Award. Since beginning his position as faculty in 2015, Dr. Boh\u00f3rquez has published 14 scientific articles, including 12 as the senior\/corresponding author. Of those, 1 is an invited review in Annual Reviews of Neuroscience and 7 are primary research articles published in journals like JCI, Cell, Nature Neuroscience, and Science.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Boh\u00f3rquez is an Associate Professor of Medicine and Neurobiology at Duke University. Dr. Boh\u00f3rquez\u2019s expertise is in gut-brain sensory transduction. This new field of sensory biology was sparked by Dr. Boh\u00f3rquez\u2019s discovery of synapses in enteroendocrine cells in 2015. Dr. Boh\u00f3rquez discovery of a sensory neuroepithelial circuit in the gut (J Clin Invest. 2015;125(2):782)\u2014analogous&#8230;<\/p>\n","protected":false},"author":3,"featured_media":4087,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4093","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/posts\/4093","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/comments?post=4093"}],"version-history":[{"count":1,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/posts\/4093\/revisions"}],"predecessor-version":[{"id":4094,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/posts\/4093\/revisions\/4094"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/media\/4087"}],"wp:attachment":[{"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/media?parent=4093"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/categories?post=4093"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/event.roseliassociates.com\/2022-us-japan-brcp\/wp-json\/wp\/v2\/tags?post=4093"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}